Cochrane's Future of Evidence Synthesis Programme: A Transformation
The arrival of 2025 means that we are now wrapping up our Future of Evidence Synthesis Programme, with several projects now closed and a few more due to wrap up by April 2025.
All aspects of the programme were designed to ensure that Cochrane is well-placed to meet rapidly shifting needs and challenges in global healthcare. It has been an ambitious programme that has introduced some important changes to how Cochrane develops, publishes, and shares its reviews.
A New Model for Synthesising Evidence
At the heart of this transformation is Cochrane’s new model for producing Cochrane evidence syntheses. The model retains many of the strengths that Cochrane’s reputation has been built on and added some new elements that will help to ensure Cochrane is sustainable and focused on major global health challenges now and into the future.
Evidence Synthesis Units and Thematic Groups
A key structural change has been the creation of Cochrane Evidence Synthesis Units and Thematic Groups, to help us address the world’s urgent health challenges more efficiently and collaboratively.
Cochrane Thematic Groups are topic-based collectives with specialist knowledge and expertise. They help identify priority areas, engage with key stakeholders, harness Cochrane’s global volunteer network and support the production and dissemination of high-quality Cochrane evidence syntheses. We have set up twelve Thematic Groups, each led by experts in their respective fields. Find out more.
Cochrane Evidence Synthesis Units are collaborative, multi-topic research groups, created to support delivery of trusted, timely Cochrane evidence to address major global health challenges. The geographic spread of the five new units reflects Cochrane’s commitment to producing evidence that helps to improve people’s health worldwide. Find out more.
Centralised Editorial Service
Cochrane’s Central Editorial Service has been scaled up to ensure an independent, and rigorous quality assurance process across all manuscripts and a more consistent experience for author teams. The Editorial Service works with Cochrane group members who contribute their expertise throughout the peer review process. Importantly, the centralisation eliminates conflicts of interest, with clear separation between manuscript development and editorial decisions. This ensures Cochrane reviews remain impartial, credible, and scientifically robust.
Simplifying the author journey
Cochrane’s authors are critical to Cochrane success – past and future – so through the Future of Evidence Synthesis programme we have introduced tools to make their experience smoother. The adoption of the Focused Review Format prioritises simplicity and clarity in review writing. This format reduces complexity for authors, speeds up review development time, and ensures Cochrane reviews communicate a clear message.
A major upgrade to RevMan, Cochrane’s authoring platform, has also taken place. The introduction of ‘study centric data’ streamlines data management, enabling authors to easily enter, reuse, and export data, reducing errors and saving time. Gone are the days of cumbersome back-and-forth data handling; authors can now focus on crafting compelling, well-supported reviews that inform global health decisions. Cochrane has expanded its resources for authors with dedicated roles, such as Evidence Synthesis Development Editors, to guide authors of high-priority review from planning to submission and offer expert advice on everything from scoping reviews to evaluating evidence quality. This hands-on assistance ensures Cochrane’s highest-priority reviews meet the highest standards while maintaining a personal touch.
Updated reporting standards and improved accessibility
A shift to the PRISMA guidelines for systematic reviews signals another step forward. Cochrane reviews now align with international standards, making them easier to produce and more user-friendly for their global audience. This transition reduces administrative burden while enhancing the clarity and accessibility of Cochrane’s output.
Additionally, systematic reviews produced in RevMan now come with downloadable data packages in formats like CSV, broadening the potential for research collaboration and reducing duplication. These changes solidify Cochrane’s commitment to Open Science, making its data transparent and accessible for the wider research community.
Global impact and inclusivity
With a renewed focus on inclusivity Cochrane seeks to ensure that its evidence reaches and benefits people everywhere. Evidence Synthesis Units in regions such as Nigeria and India reflect a deeper commitment to continue ensuring that our geographic representation in evidence synthesis is widespread and equal. Collaborations with global organisations like the World Health Organization (WHO) and local stakeholders in lower- and middle-income countries guarantee that Cochrane’s work addresses health inequities and meets diverse regional needs.
Inclusivity extends into the review process itself. With improved tools and simplified reporting standards, researchers from underrepresented regions and early-career scientists face fewer procedural barriers, increasing opportunities for collaboration and contribution to prioritise reviews that tackle globally significant issues.
Toward a brighter future for health evidence
The changes implemented as part of the Future of Evidence Synthesis Programme are not just about improving internal efficiencies, they are about creating a lasting impact. By adapting to a fast-changing scientific landscape, Cochrane can continue to contribute meaningfully to global health challenges now and in the future.
At a time of significant uncertainty, the Cochrane community has played an important role in the transformation. Together, community members have shown great resilience, ensuring these improvements address the real-world needs of practitioners, policymakers, and patients. These advancements not only secure Cochrane’s future but reaffirm its role as a bedrock of reliable health evidence in an uncertain world. For everyone who relies on trusted, accessible, and impactful health evidence, the changes brought by the Future of Evidence Synthesis programme are already making a difference. Cochrane is now better equipped than ever to deliver on its mission of improving health decisions - and people’s lives - worldwide.
Wednesday, January 15, 2025