Key messages• The two most common tests (serum or plasma retinol and retinol-binding protein) cannot reliably identify at-risk individuals with or without vitamin A deficiency in the community or clinics.• This may mean that using these tests could lead to over- or underestimated levels of low vitamin A at the population level and incorrect diagnosis of individuals.• Estimates of test accuracy should improve as more studies become available.

For over 30 years, the Cochrane Collaboration has set the standard for systematic reviews in health research.

Key messagesClinical staff should be aware that the available rating scales for assessing pain in newborn infants are of very low quality. There is a need to develop these scales further.

Key messagesRisperidone and aripiprazole may reduce irritability symptoms, while lurasidone probably results in little to no difference in children with autism.There is significant uncertainty about the effects of these drugs on aggression, weight gain and abnormal body movements (e.g. tremors) in children with autism.These medicines may decrease obsessive-compulsive symptoms (unwanted thoughts (obsessions) and repetitive behaviours (compulsions)) and inappropriate speech in children with autism.

With the UK’s National Health Service facing critical workforce shortages, the Royal College of Anaesthetists (RCoA)

Key messagesMulticomponent implementation strategies may improve adherence to World Health Organization (WHO) postpartum hemorrhage (PPH) prevention recommendations and probably do not make a difference to intensive care unit (ICU) admissions, need for additional surgeries, or death of the mother. We do not know if multicomponent implementation strategies affect blood loss or blood transfusion.

【EACA Symposium 2025 Spotlight】We are delighted to announce that Prof. Edwin Chan Shih-Yen, a leading expert in clinical epidemiology and evidence-based healthcare, will be joining us as a key speaker at the EACA Symposium 2025.

Key messages- Compared to no yoga, yoga after anticancer therapy probably reduces cancer-related fatigue slightly in the short term (up to 12 weeks after doing yoga).- We do not know if yoga during anticancer therapy relieves short-, medium-, or long-term cancer-related fatigue compared to no yoga.- More research is needed to understand (1) if the effects of starting yoga after anticancer therapy persist beyond 12 weeks, and (2) what are the effects of doing yoga before starting and during cancer treatment.