Research question What are the effects of antifibrinolytic treatment in people with aneurysmal subarachnoid haemorrhage? Background

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Only about 6% of the world’s population are native English speakers, and 75% of people don’t speak English at all. Many people do not have access to high-quality health information, because it is not available in a language that they understand. We translate Cochrane evidence to make it more accessible, and to reduce the linguistic barrier to global evidence-informed health decisions.

Key messages  1. When a patient presents with symptoms of an airway infection at the doctor's office, the doctor's use of C-reactive protein point-of-care tests during the visit probably reduces the number of patients given an antibiotic prescription, without affecting patient recovery. 2. We do not know if procalcitonin point-of-care tests have an effect on antibiotic use or patient recovery.

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Key messages Nirmatrelvir/ritonavir (Paxlovid®) is evaluated for the treatment of coronavirus disease 2019 (COVID-19). Nirmatrelvir/ritonavir may lead to fewer deaths and improve patient condition, as assessed by need for hospitalization or death within 28 days.  Data are only available for non-vaccinated people at increased risk for disease progression receiving treatment within five days of symptom onset. We found eight ongoing studies. We will update our search every month.

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Why is improving the diagnosis of tuberculosis important?

Cochrane Colloquium: London, 4-6 September 2023 Forward together for trusted evidence